Data di Pubblicazione:
1993
Citazione:
CORTICOSTERONE INCREASES FGF-2 (BFGF) IMMUNOREACTIVITY IN THE SUBSTANTIA-NIGRA OF THE RAT / Chadi, G., Rosen, L., Cintra, A., Tinner, B., Zoli, M., Pettersson, R.f., Fuxe, K.. - In: NEUROREPORT. - ISSN 0959-4965. - STAMPA. - 4:(1993), pp. 783-786. [10.1097/00001756-199306000-00045]
Abstract:
THE effects of acute and subchronic (7 days) administrations of the adrenocortical hormone corticosterone on basic fibroblast growth factor (bFGF, FGF-2) immunoreactivity were studied in the substantia nigra of the rat by semiquantitative immunocytochemistry coupled with image analysis. Corticosterone was able to increase FGF-2 immunoreactivity in different nigral subregions and cell types (astrocytes and neurones) depending on the duration of the treatment. These results open up the possibility that stress hormones can modulate the trophic state of the substantia nigra through an action on FGF-2.
Tipologia CRIS:
Articolo su rivista
Keywords:
FIBROBLAST GROWTH FACTOR; BASIC; SUBSTANTIA-NIGRA; DOPAMINE; CORTICOSTERONE; IMMUNOCYTOCHEMISTRY; IMAGE ANALYSIS
Elenco autori:
Chadi, G; Rosen, L; Cintra, A; Tinner, B; Zoli, Michele; Pettersson, Rf; Fuxe, K.
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