Clonal seborrheic keratosis: Dermoscopic and confocal microscopy characterization

Background The diagnosis of clonal seborrheic keratosis may be challenging clinically and histologically.Objective In our study, we describe the common aspects of this benign entity that show peculiar dermoscopic and confocal findings.Methods A total of nine clonal seborrheic keratosis were analyzed. Results Upon dermoscopy, it reveals the presence of globular-like structures and sharply demarcated borders whereas confocal microscopy displays the typical intraepidermal nesting of pigmented keratinocytes that permits to have a reliable in vivo diagnosis.Conclusions Dermoscopy and confocal microscopy permit to in vivo diagnose this variant of seborrheic keratosis.