Facile conversion of α,β-epoxy ketones to 2-chloro-3-hydroxy ketones by trimethylchlorosilane-dimethyl sulfoxide
Articolo
Data di Pubblicazione:
1988
Citazione:
Facile conversion of α,β-epoxy ketones to 2-chloro-3-hydroxy ketones by trimethylchlorosilane-dimethyl sulfoxide / Ghelfi, F., G., R., Pagnoni, U.M.. - In: JOURNAL OF CHEMICAL RESEARCH. SYNOPSES. - ISSN 0308-2342. - STAMPA. - /:(1988), pp. 200-201.
Abstract:
Title cleavage of epoxy ketones proceeded stereo- and regiospecifically to give 2-chloro-3-hydroxy ketones. Aryl epoxides afforded the isomeric 2-hydroxy-3-chloro ketones. Thus, treatment of epoxide I with Me3SiCl-Me2SO in MeCN at room temp. afforded 96% chlorohydrin HOCMe2CHClCOMe.
Tipologia CRIS:
Articolo su rivista
Keywords:
apertura di epossichetoni; trimetilclorosilano; dimetilsolfossido
Elenco autori:
Ghelfi, Franco; G., Romano; Pagnoni, Ugo Maria
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