Antimicrobial Testing of Schinus molle (L.) Leaf Extracts and Fractions Followed by GC-MS Investigation of Biological Active Fractions
Articolo
Data di Pubblicazione:
2020
Citazione:
Antimicrobial Testing of Schinus molle (L.) Leaf Extracts and Fractions Followed by GC-MS Investigation of Biological Active Fractions / Turchetti, G., Garzoli, S., Laghezza Masci, V., Sabia, C., Iseppi, R., Giacomello, P., Tiezzi, A., Ovidi., E.. - In: MOLECULES. - ISSN 1420-3049. - 25:8(2020), pp. 1-15. [10.3390/molecules25081977]
Abstract:
Schinus molle (L.) is a dioecious plant of the Anacardiaceae family, originating in South
America and currently widespread in many regions throughout the world. In this work leaf extracts
and derived low-pressure column chromatography (LPCC) fractions of S. molle L. male and female
plantswere investigated for the antimicrobial activity. Leaf extracts were tested on microbes Escherichia
coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, Candida albicans and Bacillus
subtilis. Furthermore, the extracts showing antimicrobial activity were fractionated by LPCC and the
obtained fractions tested on the same microorganism strains. Positive fractions were investigated
by gas-chromatography/mass spectrometry (GC-MS) and were seen to be rich in sesquiterpenes,
sesquiterpenoids and other terpens. The obtained eects highlighted the antimicrobial properties
of S. molle (L.) leaf compounds and revealed their importance as a source of bioactive molecules of
potential pharmaceutical interest. To our knowledge, this is the first paper reporting investigations on
the chemical composition of the extracts and derived positive fractions from Schinus molle (L.) plants
grown in central Italy-
America and currently widespread in many regions throughout the world. In this work leaf extracts
and derived low-pressure column chromatography (LPCC) fractions of S. molle L. male and female
plantswere investigated for the antimicrobial activity. Leaf extracts were tested on microbes Escherichia
coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, Candida albicans and Bacillus
subtilis. Furthermore, the extracts showing antimicrobial activity were fractionated by LPCC and the
obtained fractions tested on the same microorganism strains. Positive fractions were investigated
by gas-chromatography/mass spectrometry (GC-MS) and were seen to be rich in sesquiterpenes,
sesquiterpenoids and other terpens. The obtained eects highlighted the antimicrobial properties
of S. molle (L.) leaf compounds and revealed their importance as a source of bioactive molecules of
potential pharmaceutical interest. To our knowledge, this is the first paper reporting investigations on
the chemical composition of the extracts and derived positive fractions from Schinus molle (L.) plants
grown in central Italy-
Tipologia CRIS:
Articolo su rivista
Keywords:
pepper tree; antimicrobial; low-pressure column chromatography;
plant compounds; minimum inhibitory concentration; gas chromatography-mass spectrometry
Elenco autori:
Turchetti, Giovanni; Garzoli, Stefania; Laghezza Masci, Valentina; Sabia, Carla; Iseppi, Ramona; Giacomello, Pierluigi; Tiezzi, Antonio; Ovidi., Elisa
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