Health Related Quality of Life Outcomes and Length of Hospital Stay After Micro-Fragmented Autologous Adipose Tissue Injection in Minor Amputations for Diabetic Foot Ulceration (MiFrAADiF trial): Results From a Randomised Controlled Single Centre Clinical Trial

Introduction: Diabetic foot ulcer (DFU) is a high prevalence complication of diabetes mellitus that significantly impairs the health related quality of life (HRQoL) of patients and is characterised by a prolonged length of hospital stay (LOS). DFU represents a complex clinical scenario. The prevalence of diabetic foot in the global population is 6.3%. The MiFrAADiF trial demonstrated positive results in terms of the healing of DFUs after the injection of micro-fragmented autologous adipose tissue at the minor amputation stump. The impact of this technique on HRQoL and LOS versus standard care has not yet been determined.