Biological characteristics of LABLYS98, a Lactobacillus sporogenes for use as probiotic compound

Lactobacillus sporogenes (Bacillus coagulans), a spore-forming lactobacillus chosen as biological agent in a formulation for probiotic use, was cultured in media added with L-lysine monohydrochloride to increase the metabolic potentiality. The resulting strain LABLYS98 is stored at the German Collection of Microorganisms and labelled as DSM 12316. Further studies, carried out on the biological characteristics of LABLYS98, showed high stability, acid resistance, production of a large amount of lactic acid (L+) if compared with the original strain (L. sporogenes), moderate adherence to HEp-2 cells and antibacterial activity against many microorganisms used as indicators (L. monocytogenes, Enterococcus spp., A. hydrophila, etc.)