Pharmacological treatment of drug dependence in daily chronic headache sufferers

Today, treatment with drugs is the principal therapeutic defence against the different forms of primary headache. However, whilst there are many drugs of proven efficacy available for the prophylaxis of episodic headaches, treatment is much more difficult of those patients who arrive at headache centres complaining of a headache which over the yars has bevome daily and for which they have also been taking analgesic mixture every day for years without any improvement; indeed the pain has rather got worse.