Tumor necrosis factor-alpha protects synovial cells from nitric oxide induced apoptosis through phosphoinositide 3-kinase Akt signal transduction
Articolo
Data di Pubblicazione:
2006
Citazione:
Tumor necrosis factor-alpha protects synovial cells from nitric oxide induced apoptosis through phosphoinositide 3-kinase Akt signal transduction / Chen, Qingquan; Casali, Bruno; Pattacini, Laura; Boiardi, Luigi; Salvarani, Carlo. - In: THE JOURNAL OF RHEUMATOLOGY. - ISSN 0315-162X. - 33:6(2006), pp. 1061-1068.
Abstract:
To investigate the anti-apoptotic role of tumor necrosis factor-a (TNF-a) and its signaling pathways in cultured human fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis.
Tipologia CRIS:
Articolo su rivista
Keywords:
Apoptosis; Cell Survival; Chromones; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Fibroblasts; Humans; Morpholines; NF-kappa B; Nitric Oxide; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidines; Signal Transduction; Synovial Membrane; Thiocarbamates; Tumor Necrosis Factor-alpha; bcl-Associated Death Protein
Elenco autori:
Chen, Qingquan; Casali, Bruno; Pattacini, Laura; Boiardi, Luigi; Salvarani, Carlo
Link alla scheda completa:
Pubblicato in: