Data di Pubblicazione:
2012
Citazione:
Small molecule inhibitors of BRAF in clinical trials / Zambon, Alfonso; Niculescu Duvaz, Ion; Niculescu Duvaz, Dan; Marais, Richard; Springer, Caroline J.. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 22:2(2012), pp. 789-792. [10.1016/j.bmcl.2011.11.060]
Abstract:
Over the last few years, BRAF has emerged as a validated target in melanoma. This review summarises recent advances in the development of BRAF inhibitors, focussing on agents that have been assessed clinically. © 2011 Elsevier Ltd. All rights reserved.
Tipologia CRIS:
Articolo su rivista
Keywords:
BRAF protein; Clinical candidate; Kinase inhibitor; Humans; Melanoma; Molecular Weight; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Structure-Activity Relationship; Clinical Trials as Topic; 3003; Drug Discovery3003 Pharmaceutical Science; Organic Chemistry; Molecular Medicine; Molecular Biology; Clinical Biochemistry; Biochemistry
Elenco autori:
Zambon, Alfonso; Niculescu Duvaz, Ion; Niculescu Duvaz, Dan; Marais, Richard; Springer, Caroline J.
Link alla scheda completa:
Pubblicato in: