Publication Date:
2006
Short description:
NAPHTHOFURANONE DERIVATIVES AS SPECIFIC INHIBITORS OF THYMIDYLATE SYNTHASES / Costi, Maria Paola; Rossi, Tiziana; Casolari, Chiara; Tondi, Donatella; Barlocco, Daniela; Pecorari, Piergiorgio; Venturelli, Alberto.
abstract:
Synthetic compounds of 1, 2 -naphthalein molecules (I) having specific inhibitory properties of the enzymatic activity of thymidylate synthases of bacterial species, their preparation, their pharmaceutical composition and use in the treatment and prophylaxis of infectious pathologies are disclosed
Iris type:
Brevetto
Keywords:
thymidylate synthases; inhibitors; antibacterial; naphtaleine
List of contributors: