Biosensing with Electrolyte Gated Organic Field Effect Transistors

Electrolyte Gated Organic Field Effect Transistors (EGOFETs) are rapidly emerging as novel players in the field of biosensing: they allow ultra-sensitive, label-free and fast response, and can be employed to sense very diverse analytes, from small molecules to large multimeric proteins. Here, we present the current level of understanding of the working mechanism of EGOFETs, and review some of the most recent and relevant applications as sensors for healthcare and life sciences, discussing advantages and limitations of this technology. EGOFETs appear as a powerful sensing platform that can be readily adapted to the detection of a wide range of biologically relevant species.