Publication Date:
2010
Short description:
Developmental roles of the serotonin transporter / Persico, A.M. - In: Experimental Models in Serotonin Transporter Research / [a cura di] Kalueff A.V. LaPort J.L.. - GBR : Cambridge University Press, 2010. - ISBN 9780521514873. - pp. 78-104 [10.1017/CBO9780511729935.004]
abstract:
From invertebrates to humans, serotonin (5-HT) exerts structural effects especially during development. The 5-HT transporter (SERT) directly regulates these effects by maintaining extracellular 5-HT concentrations within a physiological range and possibly by modulating the intracellular redox state of the cell. This chapter addresses 5-HT trophic effects on developing neural and non-neural mammalian cells, and summarizes SERT roles in 5HT-mediated structural effects from basic neurodevelopment to human teratology.
Iris type:
Capitolo/Saggio
List of contributors:
Persico, A. M.
Book title:
Experimental Models in Serotonin Transporter Research