Defining the minimum inhibitory concentration of 22 rifamycins in iron limited, physiologic medium against Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae clinical isolates
Academic Article
Publication Date:
2023
Short description:
Defining the minimum inhibitory concentration of 22 rifamycins in iron limited, physiologic medium against Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae clinical isolates / Lu, Peggy; Alletto, Francesco; Lee, Bosul; Burk, Elizabeth; Martinez, Jasmine; Prati, Fabio; Caselli, Emilia; Spellberg, Brad; Luna, Brian. - In: PLOS ONE. - ISSN 1932-6203. - 18:6(2023), pp. e0287102-e0287102. [10.1371/journal.pone.0287102]
abstract:
: Recently, we reported rifabutin hyper-activity against Acinetobacter baumannii. We sought to characterize if any additional rifamycins (n = 22) would also display hyper-activity when tested in iron-limited media against A. baumannii, K. pneumoniae, and E. coli. MICs were determined against representative clinical isolates using the iron-limited media RPMI-1640. Only rifabutin was hyperactive against A. baumannii.
Iris type:
Articolo su rivista
List of contributors:
Lu, Peggy; Alletto, Francesco; Lee, Bosul; Burk, Elizabeth; Martinez, Jasmine; Prati, Fabio; Caselli, Emilia; Spellberg, Brad; Luna, Brian
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