Aqueous-phase quantitative NMR determination of amino acid enantiomer ratio by (13)C-NMR using chiral neodymium shift reagent
Academic Article
Publication Date:
2010
Short description:
Aqueous-phase quantitative NMR determination of amino acid enantiomer ratio by (13)C-NMR using chiral neodymium shift reagent / Florini, Nicola; Faglioni, Francesco; Zucchi, Claudia; L., Caglioti; Palyi, Gyula. - In: AMINO ACIDS. - ISSN 1438-2199. - STAMPA. - 38:5(2010), pp. 1343-1350. [10.1007/s00726-009-0341-9]
abstract:
A neodymium-(S)-PDTA (PDTA = N,N,N',N'-tetrakis[(hydroxycarbonyl)methyl]-1,2-diaminopropane) complex was found exceptionally useful in the quantitative determination of enantiomer ratios of water-soluble natural amino acids by (13)C-NMR. The method is demonstrated on mixtures of l- and d-enantiomers of various amino acids. The interactions of the chiral shift reagent with the amino acid molecules were rationalized by molecular orbital calculations.
Iris type:
Articolo su rivista
Keywords:
Analysis of amino acids, (13)C-NMR shift reagent, Neodymium complex chiral shift reagent, Water-soluble chiral shift reagent
List of contributors:
Florini, Nicola; Faglioni, Francesco; Zucchi, Claudia; L., Caglioti; Palyi, Gyula
Published in: