Publication Date:
1999
Short description:
Bile acid and hepatocyte death / M. E., G., Carubbi, F., M., C., P., M., Loria, P., Carulli, N.. - STAMPA. - (1999), pp. 49-56.
abstract:
we demonstrated that liver injury and hepatocyte death depend on the biliary bile acid composition. The effect of diferent bile acids on AST release has been shown in Hep G 2 cells. Deoxycholic and other hydrophobic bile acid toxicity can be reduced by addition of UDCA to the cell medium.
Iris type:
Monografia/Trattato scientifico
Keywords:
Cholestasis; apoptosis; hepatocyte death; liver injury; bile acids
List of contributors: