A candidate gene approach identifies an IL33 genetic variant as a novel genetic risk factor for GCA
Academic Article
Publication Date:
2014
Short description:
A candidate gene approach identifies an IL33 genetic variant as a novel genetic risk factor for GCA / Márquez, Ana; Solans, Roser; Hernández Rodríguez, José; Cid, Maria C; Castañeda, Santos; Ramentol, Marc; Rodriguez Rodriguez, Luis; Narváez, Javier; Blanco, Ricardo; Ortego Centeno, Norberto; Palm, Oyvind; Diamantopoulos, Andreas P; Braun, Niko; Moosig, Frank; Witte, Torsten; Beretta, Lorenzo; Lunardi, Claudio; Cimmino, Marco A; Vaglio, Augusto; Salvarani, Carlo; González Gay, Miguel A; Martín, Javier. - In: PLOS ONE. - ISSN 1932-6203. - 9:11(2014), pp. e113476-e113476. [10.1371/journal.pone.0113476]
abstract:
Increased expression of IL-33 and its receptor ST2, encoded by the IL1RL1 gene, has been detected in the inflamed arteries of giant cell arteritis (GCA) patients. The aim of the present study was to investigate for the first time the potential influence of the IL33 and IL1RL1 loci on GCA predisposition.
Iris type:
Articolo su rivista
List of contributors:
Márquez, Ana; Solans, Roser; Hernández Rodríguez, José; Cid, Maria C; Castañeda, Santos; Ramentol, Marc; Rodriguez Rodriguez, Luis; Narváez, Javier; Blanco, Ricardo; Ortego Centeno, Norberto; Palm, Oyvind; Diamantopoulos, Andreas P; Braun, Niko; Moosig, Frank; Witte, Torsten; Beretta, Lorenzo; Lunardi, Claudio; Cimmino, Marco A; Vaglio, Augusto; Salvarani, Carlo; González Gay, Miguel A; Martín, Javier
Published in: