Innovative ophthalmic instrument to detect nano- and micro-aggregates in blood circulation

An ophthalmic instrument for innovative analyses of the eye microcirculation is presented. The developed system employs a laser source to performs the DWS (diffusing-wave-spectroscopy) analysis of the light intensity back diffused by the ocular fundus structures, thus allowing a noninvasive detection of changes and modulations of both optical and dynamical properties of blood flow. The reported preliminary experimental results recorded in-vivo on rabbits' ocular fundus, demonstrate the ability of the system to detect nano- micro-aggregates carried by the blood flow in the ocular fundus.