Enhancement of the drug discovery process by integration of Structure-based drug design and combinatorial chemistry

Capitolo di libro
Data di Pubblicazione:
2001
Citazione:
Enhancement of the drug discovery process by integration of Structure-based drug design and combinatorial chemistry / Tondi, Donatella; Costi, Maria Paola. - STAMPA. - (2001), pp. 563-603.
Abstract:
This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists in academia and industry who offer coverage of basic principles, design strategies, methodologies, software tools and algorithms, and applications. It outlines the fundamentals of pharmacophore modelling and 3D Quantitative Structure-Activity Relationships (QSAR), classical QSAR, and target protein structure-based design methods.
Tipologia CRIS:
Capitolo/Saggio
Keywords:
HTT technologies; structure based drug design; virtual screening; libraries; combinatorial chemistry; synthesis
Elenco autori:
Autori di Ateneo:
Link alla scheda completa:
https://iris.unimore.it/handle/11380/308298
Titolo del libro:
Combinatorial library design and evaluation: principles, methods, software tools and applications for drug discovery