Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists
Articolo
Data di Pubblicazione:
1995
Citazione:
Quantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists / Menziani, Maria Cristina; Cocchi, Marina; Fanelli, Francesca; De Benedetti, Pier Giuseppe. - In: JOURNAL OF MOLECULAR STRUCTURE. THEOCHEM. - ISSN 0166-1280. - STAMPA. - 333:(1995), pp. 243-248. [10.1016/0166-1280(94)03939-I]
Abstract:
The application of molecular modelling and regression analysis techniques to the complexes between the ET(A) and ET(B) receptors and a series of C-terminal endothelin hexapeptide antagonists allowed the identification of the structural determinants for recognition and the quantitative elucidation of the receptor structure-affinity/selectivity relationships.
Tipologia CRIS:
Articolo su rivista
Keywords:
QSAR; ENDOTHELIN Receptor; ANTAGONISTS; molecular modelling
Elenco autori:
Menziani, Maria Cristina; Cocchi, Marina; Fanelli, Francesca; De Benedetti, Pier Giuseppe
Link alla scheda completa:
Pubblicato in: