INTRAVENOUS HIGH-DOSE IMMUNOGLOBULIN TREATMENT IN RECENT ONSET CHILDHOOD NARCOLEPSY WITH CATAPLEXY
Articolo
Data di Pubblicazione:
2008
Citazione:
INTRAVENOUS HIGH-DOSE IMMUNOGLOBULIN TREATMENT IN RECENT ONSET CHILDHOOD NARCOLEPSY WITH CATAPLEXY / Plazzi, Giuseppe; Poli, Francesca; Franceschini, Christian; Parmeggiani, Antonia; Pirazzoli, Piero; Bernardi, Filippo; E., Mignot; Cicognani, Alessandro; Montagna, Pasquale. - In: JOURNAL OF NEUROLOGY. - ISSN 0340-5354. - 255:10(2008), pp. 1549-1554. [10.1007/s00415-008-0983-7]
Abstract:
We report on the outcome
of intravenous high-dose
immunoglobulin (IVIg) treatment
in four children with narcolepsy
and cataplexy, in whom the early
diagnosis and the extreme disease
severity were indications for this
potentially efficacious therapy. One
of four patients showed an objective
and persistent improvement in
clinical features during and after
IVIg treatment. Our data partially
support the recent report of the
efficacy of IVIg treatment in early
diagnosed narcolepsy with cataplexy
and support the need for a
controlled multicenter clinical trial
on IVIg in narcolepsy.
Tipologia CRIS:
Articolo su rivista
Keywords:
narcolepsy with
cataplexy · intravenous
immunoglobulins · early treatment
Elenco autori:
Plazzi, Giuseppe; Poli, Francesca; Franceschini, Christian; Parmeggiani, Antonia; Pirazzoli, Piero; Bernardi, Filippo; E., Mignot; Cicognani, Alessandro; Montagna, Pasquale
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