Evaluation of in vitro absorption capacity of glyceraldehyde cross-linked gelatin microspheres

The absorption properties of glyceraldehyde cross-linked gelatin microspheres was compared in vitro with those of dextranomer or cadexomeriodine microspheres, which are used to draw up exudates and other particles away from wounds. The volume of the liquid absorbed was evaluated using both the microscopic observation of the particle swelling and the Enslin apparatus. Both the methods showed the highest absorption capacity of the glyceraldehyde cross-linked gelatin microspheres, which can be therefore proposed as a mechanical agent for cleansing the exudating wounds and ulcers.