How genetic traits may influence the dermoscopic and confocal morphology of nevi

Currently nevi can be characterized in relation to their demographics, evolution, clinical and dermoscopic morphology, genetics, and associated risk of melanoma development. The recent introduction of reflectance confocal microscopy (RCM) has opened a new morphologic dimension of melanocytic nevi; this along with recent progresses in our understanding of the molecular pathways and genetic traits involved in nevogenesis opened new ways to classify nevi and link peculiar morphologic aspects with patient phenotype.