The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resisten human T-acute leukemia cells by a JNK-dependent mechanism

The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resisten human T-acute leukemia cells by a JNK-dependent mechanism / Chiarini, Francesca; Del Sole, Marianna; Mongiorgi, Sara; Gaboardi, Gian Carlo; Cappellini, A.; Mantovani, Irina; Follo, Matilde Yung; Mccubrey, J. A.; Martelli, Alberto Maria. - In: LEUKEMIA. - ISSN 0887-6924. - 22:6(2008), pp. 1106-1116. [10.1038/leu.2008.79]