Excited-State Dynamics of bis-dehydroxycurcumin Carboxylic Acid, a Water-Soluble Derivative of the Photosensitizer Curcumin.
Articolo
Data di Pubblicazione:
2012
Citazione:
Excited-State Dynamics of bis-dehydroxycurcumin Carboxylic Acid, a Water-Soluble Derivative of the Photosensitizer Curcumin / Nardo, L., Maspero, A., Selva, M., Bondani, M., Palmisano, G., Ferrari, E., Saladini, M.. - In: JOURNAL OF PHYSICAL CHEMISTRY. A, MOLECULES, SPECTROSCOPY, KINETICS, ENVIRONMENT, & GENERAL THEORY. - ISSN 1089-5639. - STAMPA. - 116:37(2012), pp. 9321-9330. [10.1021/jp307928a]
Abstract:
Bis-dehydroxycurcumin carboxylic acid (K2A23) is a synthetic
curcuminoid designed to exhibit enhanced water solubility and photosensitizing potential with respect to natural curcumin. In this work, the tendency of the compound to form intra- and intermolecular hydrogen bonds in the ground state is studied by UV−visible absorption and by nuclear magnetic resonance
(NMR). The excited-state dynamics of the drug are probed in different environments by means of time-correlated single-photon counting measurements and related to its hydrogen bonding affinity in the excited state.
curcuminoid designed to exhibit enhanced water solubility and photosensitizing potential with respect to natural curcumin. In this work, the tendency of the compound to form intra- and intermolecular hydrogen bonds in the ground state is studied by UV−visible absorption and by nuclear magnetic resonance
(NMR). The excited-state dynamics of the drug are probed in different environments by means of time-correlated single-photon counting measurements and related to its hydrogen bonding affinity in the excited state.
Tipologia CRIS:
Articolo su rivista
Keywords:
Curcumin; Excited-State Dynamics; Bis-dehydroxycurcumin Carboxylic Acid
Elenco autori:
Nardo, Luca; Maspero, Angelo; Selva, Marco; Bondani, Maria; Palmisano, Giovanni; Ferrari, Erika; Saladini, Monica
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