Obesity and reduction of the response rate to anti-tumor necrosis factor α in rheumatoid arthritis: an approach to a personalized medicine
Articolo
Data di Pubblicazione:
2013
Citazione:
Obesity and reduction of the response rate to anti-tumor necrosis factor α in rheumatoid arthritis: an approach to a personalized medicine / Gremese, E., Carletto, A., Padovan, M., Atzeni, F., Raffeiner, B., Giardina, A.R., Favalli, E.G., Erre, G.L., Gorla, R., Galeazzi, M., Foti, R., Cantini, F., Salvarani, C., Olivieri, I., Lapadula, G., Ferraccioli, G.. - In: ARTHRITIS CARE & RESEARCH. - ISSN 2151-4658. - 65:1(2013), pp. 94-100. [10.1002/acr.21768]
Abstract:
Obesity is a mild, long-lasting inflammatory disease and, as such, could increase the inflammatory burden of rheumatoid arthritis (RA). The study aim was to determine whether obesity represents a risk factor for a poor remission rate in RA patients requiring anti-tumor necrosis factor α (anti-TNFα) therapy for progressive and active disease despite treatment with methotrexate or other disease-modifying antirheumatic drugs.
Tipologia CRIS:
Articolo su rivista
Keywords:
Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Individualized Medicine; Longitudinal Studies; Male; Middle Aged; Obesity; Receptors, Tumor Necrosis Factor; Registries; Remission Induction; Treatment Outcome; Tumor Necrosis Factor-alpha
Elenco autori:
Gremese, Elisa; Carletto, Antonio; Padovan, Melissa; Atzeni, Fabiola; Raffeiner, Bernd; Giardina, Anna Rita; Favalli, Ennio Giulio; Erre, Gian Luca; Gorla, Roberto; Galeazzi, Mauro; Foti, Rosario; Cantini, Fabrizio; Salvarani, Carlo; Olivieri, Ignazio; Lapadula, Giovanni; Ferraccioli, Gianfranco
Link alla scheda completa:
Pubblicato in: