Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with {NAFLD}
Articolo
Data di Pubblicazione:
2021
Citazione:
Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with {NAFLD} / Corradini, Elena; Buzzetti, Elena; Dongiovanni, Paola; Scarlini, Stefania; Caleffi, Angela; Pelusi, Serena; Bernardis, Isabella; Ventura, Paolo; Rametta, Raffaela; Tenedini, Elena; Tagliafico, Enrico; Ludovica Fracanzani, Anna; Fargion, Silvia; Pietrangelo, Antonello; Vittorio Valenti, Luca. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - 75:3(2021), pp. 506-513. [10.1016/j.jhep.2021.03.014]
Abstract:
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disorder resulting from genetic and environmental factors. Hyperferritinemia has been associated with increased hepatic iron stores and worse outcomes in patients with NAFLD. The aim of this study was to evaluate the prevalence of variants of iron-related genes and their association with hyperferritinemia, hepatic iron stores and liver disease severity in patients with NAFLD.
Tipologia CRIS:
Articolo su rivista
Keywords:
ceruloplasmin; ferritin; iron; next generation sequencing; non-alcoholic fatty liver disease
Elenco autori:
Corradini, Elena; Buzzetti, Elena; Dongiovanni, Paola; Scarlini, Stefania; Caleffi, Angela; Pelusi, Serena; Bernardis, Isabella; Ventura, Paolo; Rametta, Raffaela; Tenedini, Elena; Tagliafico, Enrico; Ludovica Fracanzani, Anna; Fargion, Silvia; Pietrangelo, Antonello; Vittorio Valenti, Luca
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