GRADE Guidance article 35: Update on rating imprecision for assessing contextualized certainty of evidence and making decisions

Articolo
Data di Pubblicazione:
2022
Citazione:
GRADE Guidance article 35: Update on rating imprecision for assessing contextualized certainty of evidence and making decisions / Schünemann, Holger J; Neumann, Ignacio; Hultcrantz, Monica; Brignardello-Petersen, Romina; Zeng, Linan; Murad, M Hassan; Izcovich, Ariel; Morgano, Gian Paolo; Baldeh, Tejan; Santesso, Nancy; Cuello, Carlos Garcia; Mbuagbaw, Lawrence; Guyatt, Gordon; Wiercioch, Wojtek; Piggott, Thomas; De Beer, Hans; Vinceti, Marco; Mathioudakis, Alexander G; Mayer, Martin G; Mustafa, Reem; Filippini, Tommaso; Iorio, Alfonso; Nieuwlaat, Robby; Marcucci, Maura; Coello, Pablo Alonso; Bonovas, Stefanos; Piovani, Daniele; Tomlinson, George; Akl, Elie A. - In: JOURNAL OF CLINICAL EPIDEMIOLOGY. - ISSN 0895-4356. - 150:(2022), pp. 225-242. [10.1016/j.jclinepi.2022.07.015]
Abstract:
GRADE guidance to rate the certainty domain of imprecision is presently not fully operationalized for rating down by two levels and when different or uncertainty in baseline risks are considered. In addition, there are scenarios in which lowering the certainty of evidence by three levels for imprecision is more appropriate than lowering it by two levels. In this article, we conceptualize and operationalize rating down for imprecision by one, two and three levels for imprecision using the contextualized GRADE approaches.
Tipologia CRIS:
Articolo su rivista
Keywords:
GRADE; guidelines; imprecision; statistical significance; systematic reviews
Elenco autori:
Autori di Ateneo:
Link alla scheda completa:
https://iris.unimore.it/handle/11380/1285087
Pubblicato in:
JOURNAL OF CLINICAL EPIDEMIOLOGY
Journal