Data di Pubblicazione:
2008
Citazione:
Total synthesis of a dienynone from Echinacea pallida / S., M., Pellati, F., Benvenuti, S., Prati, F.. - In: TETRAHEDRON. - ISSN 0040-4020. - STAMPA. - 64:27(2008), pp. 6324-6328. [10.1016/j.tet.2008.04.094]
Abstract:
The first total synthesis of (8Z,13Z)-pentadeca-8,13-dien-11-yn-2-one is described. This dienynone was recently isolated from the n-hexane extract of Echinacea pallida roots and displayed a selective cytotoxic activity toward cancer cells, thus featuring as a potential anticancer lead. The product was obtained in 11 steps in 25% overall yield.
Tipologia CRIS:
Articolo su rivista
Keywords:
Echinacea pallida; total synthesis; acetylenes; polyenes; cytotoxicity
Elenco autori:
S., Morandi; Pellati, Federica; Benvenuti, Stefania; Prati, Fabio
Link alla scheda completa:
Pubblicato in: